
Spinal Manipulative
Therapy for Low Back Pain
A
Meta-Analysis of Effectiveness Relative to Other Therapies
Willem J.J. Assendelft, MD, PhD; Sally C. Morton, PhD; Emily I. Yu, MPH;
Marika J. Suttorp, MS; and Paul G. Shekelle, MD, PhD, Pages 871–881
Background: Low
back pain is a costly illness for which spinal manipulative therapy is
commonly recommended. Previous systematic reviews and practice
guidelines have reached discordant results on the effectiveness of this
therapy for low back pain.
Purpose: To
resolve the discrepancies related to use of spinal manipulative therapy
and to update previous estimates of effectiveness by comparing spinal
manipulative therapy with other therapies and then incorporating data
from recent high-quality randomized, controlled trials (RCTs) into the
analysis.
Data Sources: MEDLINE,
EMBASE, CINAHL, the Cochrane Controlled Trials Register, and previous
systematic reviews.
Study Selection: Randomized,
controlled trials of patients with low back pain that evaluated spinal
manipulative therapy with at least 1 day of follow-up and at least one
clinically relevant outcome measure.
Data Extraction: Two
authors, who served as the reviewers for all stages of the
meta-analysis, independently extracted data from unmasked articles.
Comparison treatments were classified into the following seven
categories: sham, conventional general practitioner care, analgesics,
physical therapy, exercises, back school, or a collection of therapies
judged to be ineffective or even harmful (traction, corset, bed rest,
home care, topical gel, no treatment, diathermy, and minimal massage).
Data Synthesis: Thirty-nine
RCTs were identified. Meta-regression models were developed for acute or
chronic pain and short-term and long-term pain and function. For
patients with acute low back pain, spinal manipulative therapy was
superior only to sham therapy (10-mm difference [95% CI, 2 to 17 mm] on
a 100-mm visual analogue scale) or therapies judged to be ineffective or
even harmful.
Spinal manipulative therapy had no statistically or clinically
significant advantage over general practitioner care, analgesics,
physical therapy, exercises, or back school.
Results for patients with chronic low back pain were similar. Radiation
of pain, study quality, profession of manipulator, and use of
manipulation alone or in combination with other therapies did not affect
these results.
Conclusions: There
is no evidence that spinal manipulative therapy is superior to other
standard treatments for patients with acute or chronic low back pain.
Ann
Intern Med. 2003;138:871–881.